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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA desaturase 1' and Ligand = 'BDBM50304949'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Mus musculus)		BDBM50304949
PNG
(CHEMBL591563 | N-(2-(2-fluorophenyl)-2-hydroxyethy...)
Show SMILES Cc1ccccc1C(=O)C1CCN(CC1)c1ccc(nn1)C(=O)NCC(O)c1ccccc1F
Show InChI InChI=1S/C26H27FN4O3/c1-17-6-2-3-7-19(17)25(33)18-12-14-31(15-13-18)24-11-10-22(29-30-24)26(34)28-16-23(32)20-8-4-5-9-21(20)27/h2-11,18,23,32H,12-16H2,1H3,(H,28,34)
PDB

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PC sid
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Similars
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Daiichi Sankyo Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins

Bioorg Med Chem Lett 20: 341-5 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7
More data for this
Ligand-Target Pair