Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50185934 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16.4 | -44.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
National Institutes of Health | Assay Description Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. | Chem Biol 12: 237-47 (2005) Article DOI: 10.1016/j.chembiol.2004.12.010 BindingDB Entry DOI: 10.7270/Q2P26WK5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50185934 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.18E+3 | -33.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
National Institutes of Health | Assay Description Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. | Chem Biol 12: 237-47 (2005) Article DOI: 10.1016/j.chembiol.2004.12.010 BindingDB Entry DOI: 10.7270/Q2P26WK5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50185934 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health | Assay Description Binding affinity of ligand at human adenosine receptors expressed in CHO cell. | Chem Biol 12: 237-47 (2005) Article DOI: 10.1016/j.chembiol.2004.12.010 BindingDB Entry DOI: 10.7270/Q2P26WK5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50185934 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10E+4 | -28.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
National Institutes of Health | Assay Description Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. | Chem Biol 12: 237-47 (2005) Article DOI: 10.1016/j.chembiol.2004.12.010 BindingDB Entry DOI: 10.7270/Q2P26WK5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50185934 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.28E+4 | -25.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
National Institutes of Health | Assay Description Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. | Chem Biol 12: 237-47 (2005) Article DOI: 10.1016/j.chembiol.2004.12.010 BindingDB Entry DOI: 10.7270/Q2P26WK5 | |||||||||||
More data for this Ligand-Target Pair |