Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50150077 (2-((1H-imidazol-2-yl)methylthio)-6-amino-4-phenylp...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]PSB-11 from human A3 receptor expressed in CHO cell membranes measured after 3 hrs by radioligand binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01856 BindingDB Entry DOI: 10.7270/Q2PN99H7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50150077 (2-((1H-imidazol-2-yl)methylthio)-6-amino-4-phenylp...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 171 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leiden Curated by ChEMBL | Assay Description Binding affinity against human adenosine A3 receptor expressed on HEK293 cells using [125I]I-AB-MECA | J Med Chem 47: 3707-9 (2004) Article DOI: 10.1021/jm049947s BindingDB Entry DOI: 10.7270/Q2833SS3 | |||||||||||
More data for this Ligand-Target Pair |