Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 10' and Ligand = 'BDBM492902'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM492902 (US10981899, Example RU-0204277-LRE1) Show SMILES Nc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1 Show InChI InChI=1S/C12H13ClN4S/c13-10-6-11(16-12(14)15-10)17(8-3-4-8)7-9-2-1-5-18-9/h1-2,5-6,8H,3-4,7H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM492902 (US10981899, Example RU-0204277-LRE1) Show SMILES Nc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1 Show InChI InChI=1S/C12H13ClN4S/c13-10-6-11(16-12(14)15-10)17(8-3-4-8)7-9-2-1-5-18-9/h1-2,5-6,8H,3-4,7H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Tri-Institutional Therapeutics Discovery Institute US Patent					Assay Description The RapidFire 365 High-throughput MS System (Agilent Technologies; RF-MSS) can process samples every 15 seconds allowing analysis of a 384 well plate...				US Patent US10981899 (2021) BindingDB Entry DOI: 10.7270/Q2WD43Q0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM492902 (US10981899, Example RU-0204277-LRE1) Show SMILES Nc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1 Show InChI InChI=1S/C12H13ClN4S/c13-10-6-11(16-12(14)15-10)17(8-3-4-8)7-9-2-1-5-18-9/h1-2,5-6,8H,3-4,7H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Tri-Institutional Therapeutics Discovery Institute US Patent					Assay Description INS-1E insulinoma cells were incubated in 2.5 mM glucose Krebs-Ringer buffer (pH 7.5) supplemented with 2 mM sodium bicarbonate, 10 mM HEPES, and 0.1...				US Patent US10981899 (2021) BindingDB Entry DOI: 10.7270/Q2WD43Q0
					More data for this Ligand-Target Pair				3D Structure (crystal)