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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50006462'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50006462
PNG
((3-Benzothiazol-2-ylmethyl-4-oxo-3,4-dihydro-benzo...)
Show SMILES OC(=O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc3ccccc3cc12
Show InChI InChI=1S/C22H15N3O3S/c26-21(27)11-18-15-9-13-5-1-2-6-14(13)10-16(15)22(28)25(24-18)12-20-23-17-7-3-4-8-19(17)29-20/h1-10H,11-12H2,(H,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 46n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase isolated from human placenta

J Med Chem 35: 2155-62 (1992)


BindingDB Entry DOI: 10.7270/Q2KK99RR
More data for this
Ligand-Target Pair