Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50006477'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006477 (CHEMBL419254 | [5-Chloro-1-(5,7-difluoro-benzothia...) Show SMILES OC(=O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c2ccc(Cl)cc12 Show InChI InChI=1S/C17H10ClF2N3O2S/c18-8-1-2-14-10(3-8)12(6-16(24)25)22-23(14)7-15-21-13-5-9(19)4-11(20)17(13)26-15/h1-5H,6-7H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase isolated from human placenta				J Med Chem 35: 2155-62 (1992) BindingDB Entry DOI: 10.7270/Q2KK99RR
					More data for this Ligand-Target Pair