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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50009823'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50009823
PNG
((3-Benzothiazol-2-ylmethyl-7-methoxy-4-oxo-3,4-dih...)
Show SMILES COc1ccc2c(c1)c(CC(O)=O)nn(Cc1nc3ccccc3s1)c2=O
Show InChI InChI=1S/C19H15N3O4S/c1-26-11-6-7-12-13(8-11)15(9-18(23)24)21-22(19(12)25)10-17-20-14-4-2-3-5-16(14)27-17/h2-8H,9-10H2,1H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 28n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.

J Med Chem 34: 108-22 (1991)


BindingDB Entry DOI: 10.7270/Q2513X6H
More data for this
Ligand-Target Pair