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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1 [K65Q]' and Ligand = 'BDBM50038848'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1 [K65Q]


(Bos taurus (Cattle))		BDBM50038848
PNG
(2-(4-bromo-2-fluorobenzyl)-7-chloro-1H,2'H,5'H-spi...)
Show SMILES Fc1cc(Br)ccc1CN1C(=O)c2cc(Cl)ccc2C2(CC(=O)NC2=O)C1=O
Show InChI InChI=1S/C19H11BrClFN2O4/c20-10-2-1-9(14(22)5-10)8-24-16(26)12-6-11(21)3-4-13(12)19(18(24)28)7-15(25)23-17(19)27/h1-6H,7-8H2,(H,23,25,27)
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n/an/a 33n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation

J Med Chem 37: 2043-58 (1994)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2BR8STM
More data for this
Ligand-Target Pair