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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1 [K65Q]' and Ligand = 'BDBM50038851'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1 [K65Q]


(Bos taurus (Cattle))		BDBM50038851
PNG
(2-[3-(trifluoromethyl)benzyl]-1H,2'H,5'H-spiro[iso...)
Show SMILES FC(F)(F)c1cccc(CN2C(=O)c3ccccc3C3(CC(=O)NC3=O)C2=O)c1
Show InChI InChI=1S/C20H13F3N2O4/c21-20(22,23)12-5-3-4-11(8-12)10-25-16(27)13-6-1-2-7-14(13)19(18(25)29)9-15(26)24-17(19)28/h1-8H,9-10H2,(H,24,26,28)
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 17n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation

J Med Chem 37: 2043-58 (1994)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2BR8STM
More data for this
Ligand-Target Pair