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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1 [K65Q]' and Ligand = 'BDBM50038853'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1 [K65Q]


(Bos taurus (Cattle))		BDBM50038853
PNG
(2-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]meth...)
Show SMILES FC(F)(F)c1ccc2sc(CN3C(=O)c4ccccc4C4(CC(=O)NC4=O)C3=O)nc2c1
Show InChI InChI=1S/C21H12F3N3O4S/c22-21(23,24)10-5-6-14-13(7-10)25-16(32-14)9-27-17(29)11-3-1-2-4-12(11)20(19(27)31)8-15(28)26-18(20)30/h1-7H,8-9H2,(H,26,28,30)
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PubMed
n/an/a 22n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation

J Med Chem 37: 2043-58 (1994)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2BR8STM
More data for this
Ligand-Target Pair