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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1 [K65Q]' and Ligand = 'BDBM50038855'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1 [K65Q]


(Bos taurus (Cattle))		BDBM50038855
PNG
(2-(4-bromo-2-fluorobenzyl)-6-(trifluoromethyl)-1H,...)
Show SMILES Fc1cc(Br)ccc1CN1C(=O)c2ccc(cc2C2(CC(=O)NC2=O)C1=O)C(F)(F)F
Show InChI InChI=1S/C20H11BrF4N2O4/c21-11-3-1-9(14(22)6-11)8-27-16(29)12-4-2-10(20(23,24)25)5-13(12)19(18(27)31)7-15(28)26-17(19)30/h1-6H,7-8H2,(H,26,28,30)
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 38n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation

J Med Chem 37: 2043-58 (1994)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2BR8STM
More data for this
Ligand-Target Pair