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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' and Ligand = 'BDBM50234703'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus (Cattle))		BDBM50234703
PNG
(CHEMBL4104578)
Show SMILES CCc1ccc(cc1)-c1c(-c2ccc(C)cc2)n(Cc2ccc(OC)cc2)c2ccc(cc2c1=O)[N+]([O-])=O
Show InChI InChI=1S/C32H28N2O4/c1-4-22-7-13-24(14-8-22)30-31(25-11-5-21(2)6-12-25)33(20-23-9-16-27(38-3)17-10-23)29-18-15-26(34(36)37)19-28(29)32(30)35/h5-19H,4,20H2,1-3H3
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Article
PubMed
n/an/a 1.66E+3n/an/an/an/an/an/a



Universit£t Rostock

Curated by ChEMBL


Assay Description
Inhibition of bovine TNAP using CDP-star as substrate preincubated for 5 to 7 mins followed by substrate addition measured after 15 mins by spectroph...

Eur J Med Chem 126: 408-420 (2017)


Article DOI: 10.1016/j.ejmech.2016.11.036
BindingDB Entry DOI: 10.7270/Q2DZ0BKR
More data for this
Ligand-Target Pair