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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' and Ligand = 'BDBM50234704'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus (Cattle))		BDBM50234704
PNG
(CHEMBL4096018)
Show SMILES COc1ccc(Cn2c(-c3ccc(C)cc3)c(-c3cc(C)cc(C)c3)c(=O)c3cc(ccc23)[N+]([O-])=O)cc1
Show InChI InChI=1S/C32H28N2O4/c1-20-5-9-24(10-6-20)31-30(25-16-21(2)15-22(3)17-25)32(35)28-18-26(34(36)37)11-14-29(28)33(31)19-23-7-12-27(38-4)13-8-23/h5-18H,19H2,1-4H3
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 4.74E+3n/an/an/an/an/an/a



Universit£t Rostock

Curated by ChEMBL


Assay Description
Inhibition of bovine TNAP using CDP-star as substrate preincubated for 5 to 7 mins followed by substrate addition measured after 15 mins by spectroph...

Eur J Med Chem 126: 408-420 (2017)


Article DOI: 10.1016/j.ejmech.2016.11.036
BindingDB Entry DOI: 10.7270/Q2DZ0BKR
More data for this
Ligand-Target Pair