Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM235179'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235179 (US9365558, 2 | US9365558, 33 | US9822074, 33) Show SMILES Cc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(C#CCCCCCC(F)(F)F)C(F)(F)F |r,c:8| Show InChI InChI=1S/C25H26F6N2O4S/c1-16-7-9-17(10-8-16)19-15-23(25(29,30)31,13-5-3-2-4-6-14-24(26,27)28)32-21(34)20(19)22(35)33-38(36,37)18-11-12-18/h7-10,18H,2-4,6,11-12,14-15H2,1H3,(H,32,34)(H,33,35)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235179 (US9365558, 2 | US9365558, 33 | US9822074, 33) Show SMILES Cc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(C#CCCCCCC(F)(F)F)C(F)(F)F |r,c:8| Show InChI InChI=1S/C25H26F6N2O4S/c1-16-7-9-17(10-8-16)19-15-23(25(29,30)31,13-5-3-2-4-6-14-24(26,27)28)32-21(34)20(19)22(35)33-38(36,37)18-11-12-18/h7-10,18H,2-4,6,11-12,14-15H2,1H3,(H,32,34)(H,33,35)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235179 (US9365558, 2 | US9365558, 33 | US9822074, 33) Show SMILES Cc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(C#CCCCCCC(F)(F)F)C(F)(F)F |r,c:8| Show InChI InChI=1S/C25H26F6N2O4S/c1-16-7-9-17(10-8-16)19-15-23(25(29,30)31,13-5-3-2-4-6-14-24(26,27)28)32-21(34)20(19)22(35)33-38(36,37)18-11-12-18/h7-10,18H,2-4,6,11-12,14-15H2,1H3,(H,32,34)(H,33,35)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair