Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM235180'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235180 (US9365558, 3 | US9822074, 3) Show SMILES Cc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ncc(CCCCCCC(F)(F)F)s1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C27H29F6N3O4S2/c1-16-7-9-17(10-8-16)20-14-25(27(31,32)33,35-22(37)21(20)23(38)36-42(39,40)19-11-12-19)24-34-15-18(41-24)6-4-2-3-5-13-26(28,29)30/h7-10,15,19H,2-6,11-14H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235180 (US9365558, 3 | US9822074, 3) Show SMILES Cc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ncc(CCCCCCC(F)(F)F)s1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C27H29F6N3O4S2/c1-16-7-9-17(10-8-16)20-14-25(27(31,32)33,35-22(37)21(20)23(38)36-42(39,40)19-11-12-19)24-34-15-18(41-24)6-4-2-3-5-13-26(28,29)30/h7-10,15,19H,2-6,11-14H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair