Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM235219'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235219 (US9365558, 42 | US9365558, 49 | US9822074, 42) Show SMILES CC(C)n1ccc(n1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1F)C(F)(F)F |r,c:9| Show InChI InChI=1S/C26H27F7N4O5S/c1-14(2)37-10-8-20(35-37)17-13-24(26(31,32)33,34-22(38)21(17)23(39)36-43(40,41)16-5-6-16)18-7-4-15(12-19(18)27)42-11-3-9-25(28,29)30/h4,7-8,10,12,14,16H,3,5-6,9,11,13H2,1-2H3,(H,34,38)(H,36,39)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235219 (US9365558, 42 | US9365558, 49 | US9822074, 42) Show SMILES CC(C)n1ccc(n1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1F)C(F)(F)F |r,c:9| Show InChI InChI=1S/C26H27F7N4O5S/c1-14(2)37-10-8-20(35-37)17-13-24(26(31,32)33,34-22(38)21(17)23(39)36-43(40,41)16-5-6-16)18-7-4-15(12-19(18)27)42-11-3-9-25(28,29)30/h4,7-8,10,12,14,16H,3,5-6,9,11,13H2,1-2H3,(H,34,38)(H,36,39)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235219 (US9365558, 42 | US9365558, 49 | US9822074, 42) Show SMILES CC(C)n1ccc(n1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1F)C(F)(F)F |r,c:9| Show InChI InChI=1S/C26H27F7N4O5S/c1-14(2)37-10-8-20(35-37)17-13-24(26(31,32)33,34-22(38)21(17)23(39)36-43(40,41)16-5-6-16)18-7-4-15(12-19(18)27)42-11-3-9-25(28,29)30/h4,7-8,10,12,14,16H,3,5-6,9,11,13H2,1-2H3,(H,34,38)(H,36,39)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair