Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM235251'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235251 (US9365558, 74 | US9822074, 74) Show SMILES FC(F)(F)CCCOc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CCC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:29| Show InChI InChI=1S/C28H30F6N4O5S/c29-27(30,31)12-2-14-43-19-7-5-18(6-8-19)26(28(32,33)34)15-21(22-11-13-38(36-22)16-17-3-1-4-17)23(24(39)35-26)25(40)37-44(41,42)20-9-10-20/h5-8,11,13,17,20H,1-4,9-10,12,14-16H2,(H,35,39)(H,37,40)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235251 (US9365558, 74 | US9822074, 74) Show SMILES FC(F)(F)CCCOc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CCC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:29| Show InChI InChI=1S/C28H30F6N4O5S/c29-27(30,31)12-2-14-43-19-7-5-18(6-8-19)26(28(32,33)34)15-21(22-11-13-38(36-22)16-17-3-1-4-17)23(24(39)35-26)25(40)37-44(41,42)20-9-10-20/h5-8,11,13,17,20H,1-4,9-10,12,14-16H2,(H,35,39)(H,37,40)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair