BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor' and Ligand = 'BDBM50228237'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50228237 (CHEMBL554455) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Pharmacologie (UA 589 CNRS) Curated by ChEMBL					Assay Description Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparation				J Med Chem 32: 1402-7 (1989) BindingDB Entry DOI: 10.7270/Q2SQ92M9
Institut de Pharmacologie (UA 589 CNRS) Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50228237 (CHEMBL554455) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Pharmacologie (UA 589 CNRS) Curated by ChEMBL					Assay Description Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparation				J Med Chem 32: 1402-7 (1989) BindingDB Entry DOI: 10.7270/Q2SQ92M9
Institut de Pharmacologie (UA 589 CNRS) Curated by ChEMBL					More data for this Ligand-Target Pair