Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM35254![]() (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Richter Gedeon Nyrt. US Patent | Assay Description Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o... | US Patent US8802672 (2014) BindingDB Entry DOI: 10.7270/Q2FF3R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM35254![]() (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Intra-Cellular Therapies, Inc. Curated by ChEMBL | Assay Description Inhibition of adrenergic alpha1A receptor (unknown origin) | J Med Chem 57: 2670-82 (2014) Article DOI: 10.1021/jm401958n BindingDB Entry DOI: 10.7270/Q27D2WNZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM35254![]() (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank US Patent | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Intra-Cellular Therapies, Inc. US Patent | Assay Description Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors. | US Patent US8598119 (2013) BindingDB Entry DOI: 10.7270/Q28K77RC | |||||||||||
More data for this Ligand-Target Pair |