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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor' and Ligand = 'BDBM50226315'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor


(RAT-NEONATAL RAT-Rattus norvegicus (rat))		BDBM50226315
PNG
(CHEMBL441773)
Show SMILES CSc1c(Cl)nc(nc1NC(C)C)N1CCN(C)CC1
Show InChI InChI=1S/C13H22ClN5S/c1-9(2)15-12-10(20-4)11(14)16-13(17-12)19-7-5-18(3)6-8-19/h9H,5-8H2,1-4H3,(H,15,16,17)
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 26n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity was measured as the inhibition of [3H]clonidine binding to alpha-2 adrenergic receptor of rat cortical membranes

J Med Chem 29: 1394-8 (1986)


BindingDB Entry DOI: 10.7270/Q21R6SQQ
More data for this
Ligand-Target Pair