Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50052880![]() (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2C adrenergic receptor from cloned human C-2 receptor transfected into Chinese hamste... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50052880![]() (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2C adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50052880![]() (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Binding affinity for human Alpha-2C adrenergic receptor from cultured LM(tk-) cells using [3H]- prazosin | Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1N3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50052880![]() (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Alpha-2C adrenergic receptor agonistic potency as inhibition of forskolin-stimulated cyclic adenosine monophosphate synthesis | Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1N3J | |||||||||||
More data for this Ligand-Target Pair |