Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-mannosidase 2' and Ligand = 'BDBM84872'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-mannosidase 2 (Drosophila melanogaster (Fruit fly))	BDBM84872 (Swainsonine derivative, 7) Show SMILES CC(C)(C)c1ccc(CC[C@@H]2CC[C@@H](O)C3[C@H](O)[C@H](O)CN23)cc1 |r| Show InChI InChI=1S/C20H31NO3/c1-20(2,3)14-7-4-13(5-8-14)6-9-15-10-11-16(22)18-19(24)17(23)12-21(15)18/h4-5,7-8,15-19,22-24H,6,9-12H2,1-3H3/t15-,16-,17-,18?,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	5.75	25
University of Toronto					Assay Description Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...				Chembiochem 11: 673-80 (2010) Article DOI: 10.1002/cbic.200900750 BindingDB Entry DOI: 10.7270/Q2WS8RRM
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