Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-synuclein' and Ligand = 'BDBM170562'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM170562 (US9085549, 76) Show SMILES COc1cc(ccc1O)-c1nnc(s1)-c1cc(O)c(O)cc1I Show InChI InChI=1S/C15H11IN2O4S/c1-22-13-4-7(2-3-10(13)19)14-17-18-15(23-14)8-5-11(20)12(21)6-9(8)16/h2-6,19-21H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	219	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PROTEOTECH INC US Patent					Assay Description The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
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