Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-synuclein' and Ligand = 'BDBM207858'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207858 (US9266832, Cpd015) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cc4ccccc4)cc3)c2c1 Show InChI InChI=1S/C24H21ClN2O/c25-21-10-11-23-22(15-21)20(16-27-23)12-13-26-24(28)19-8-6-18(7-9-19)14-17-4-2-1-3-5-17/h1-11,15-16,27H,12-14H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	154	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
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