Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-synuclein' and Ligand = 'BDBM207884'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207884 (US9266832, Cpd041) Show SMILES FC(F)(F)c1ccccc1Cc1ccc(cc1)C(=O)NCCc1c[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C25H20ClF3N2O/c26-20-9-10-23-21(14-20)19(15-31-23)11-12-30-24(32)17-7-5-16(6-8-17)13-18-3-1-2-4-22(18)25(27,28)29/h1-10,14-15,31H,11-13H2,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
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