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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50353012'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50353012
PNG
(CHEMBL1821974)
Show SMILES NC1CCc2c(Cl)cccc2CC1=O
Show InChI InChI=1S/C11H12ClNO/c12-9-3-1-2-7-6-11(14)10(13)5-4-8(7)9/h1-3,10H,4-6,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
88n/an/an/an/an/an/an/an/a



Universit£ de Haute Alsace

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney APN assessed as decrease in p-nitroanilide release using L-leucine-p-nitroanilide as substrate by spectrophotometric ana...


Bioorg Med Chem 23: 3192-207 (2015)


Article DOI: 10.1016/j.bmc.2015.04.066
BindingDB Entry DOI: 10.7270/Q2Z321DW
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50353012
PNG
(CHEMBL1821974)
Show SMILES NC1CCc2c(Cl)cccc2CC1=O
Show InChI InChI=1S/C11H12ClNO/c12-9-3-1-2-7-6-11(14)10(13)5-4-8(7)9/h1-3,10H,4-6,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
90n/an/an/an/an/an/an/an/a



Universit£ de Haute Alsace

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney APN using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysis


Bioorg Med Chem 19: 5716-33 (2011)


Article DOI: 10.1016/j.bmc.2011.06.089
BindingDB Entry DOI: 10.7270/Q2805307
More data for this
Ligand-Target Pair