Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50478367'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50478367 (CHEMBL259382) Show SMILES CC[C@H](C)[C@H](NC(=O)C[C@@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C41H56N8O8/c1-5-25(4)36(48-34(51)21-28(45-38(53)35(42)24(2)3)18-27-13-15-30(50)16-14-27)39(54)46-31(20-29-22-43-23-44-29)40(55)49-17-9-12-33(49)37(52)47-32(41(56)57)19-26-10-7-6-8-11-26/h6-8,10-11,13-16,22-25,28,31-33,35-36,50H,5,9,12,17-21,42H2,1-4H3,(H,43,44)(H,45,53)(H,46,54)(H,47,52)(H,48,51)(H,56,57)/t25-,28+,31-,32-,33-,35-,36-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Brussel Curated by ChEMBL					Assay Description Inhibition of human recombinant APN expressed in HEK293 cells				J Med Chem 51: 2291-6 (2008) Article DOI: 10.1021/jm701490g BindingDB Entry DOI: 10.7270/Q25M68HP
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