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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50528324'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase N


(Homo sapiens (Human))		BDBM50528324
PNG
(CHEMBL4586126)
Show SMILES CC(C)NC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1
Show InChI InChI=1S/C25H22F3N3O4/c1-13(2)29-23(32)16-7-9-17(10-8-16)24(33)30-22(25(34)31-35)15-5-3-14(4-6-15)18-11-19(26)21(28)20(27)12-18/h3-13,22,35H,1-2H3,(H,29,32)(H,30,33)(H,31,34)
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PC cid
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Article
PubMed
 631n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...

J Med Chem 62: 7185-7209 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00757
BindingDB Entry DOI: 10.7270/Q2KK9G8J
More data for this
Ligand-Target Pair