Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50477440'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50477440 (CHEMBL245478) Show SMILES CN(C)c1ccc(\C=C\c2cc(Br)cc(\C=C\c3ccc(cc3)N(C)C)c2)cc1 Show InChI InChI=1S/C26H27BrN2/c1-28(2)25-13-9-20(10-14-25)5-7-22-17-23(19-24(27)18-22)8-6-21-11-15-26(16-12-21)29(3)4/h5-19H,1-4H3/b7-5+,8-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay				Bioorg Med Chem Lett 17: 1466-70 (2007) Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S
					More data for this Ligand-Target Pair