Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50480217'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50480217 (CHEMBL524651) Show SMILES CNc1ccc(cc1)-c1nc2c(O)cccc2s1 Show InChI InChI=1S/C14H12N2OS/c1-15-10-7-5-9(6-8-10)14-16-13-11(17)3-2-4-12(13)18-14/h2-8,15,17H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
K.U. Leuven Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta-amyloid plaques in brain homogenate of patient with Alzheimer's disease by gamma counting				Eur J Med Chem 44: 1415-26 (2009) Article DOI: 10.1016/j.ejmech.2008.09.038 BindingDB Entry DOI: 10.7270/Q25H7K2X
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