BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50094975'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alla Chem LLC Curated by ChEMBL					Assay Description Antagonist activity at androgen receptor (unknown origin)				Eur J Med Chem 99: 51-66 (2015) Article DOI: 10.1016/j.ejmech.2015.05.039 BindingDB Entry DOI: 10.7270/Q2NP265W
Alla Chem LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of androgen receptor (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112667 BindingDB Entry DOI: 10.7270/Q2HD80BX
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting a...				J Med Chem 62: 491-511 (2019) Article DOI: 10.1021/acs.jmedchem.8b00973 BindingDB Entry DOI: 10.7270/Q2GF0XZ5
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00943 BindingDB Entry DOI: 10.7270/Q2DV1PHB
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting a...				J Med Chem 62: 491-511 (2019) Article DOI: 10.1021/acs.jmedchem.8b00973 BindingDB Entry DOI: 10.7270/Q2GF0XZ5
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-R1881 from AR in human LNCaP cells preincubated for 30 mins followed by [3H]-R1881 addition measured after 30 mins by microbeta ...				Bioorg Med Chem Lett 27: 2803-2806 (2017) Article DOI: 10.1016/j.bmcl.2017.04.071 BindingDB Entry DOI: 10.7270/Q2NZ8B1S
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hr...				J Med Chem 62: 491-511 (2019) Article DOI: 10.1021/acs.jmedchem.8b00973 BindingDB Entry DOI: 10.7270/Q2GF0XZ5
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-R1881 from AR in human LNCaP cells preincubated for 30 mins followed by [3H]-R1881 addition measured after 30 mins by microbeta ...				Bioorg Med Chem Lett 27: 2803-2806 (2017) Article DOI: 10.1016/j.bmcl.2017.04.071 BindingDB Entry DOI: 10.7270/Q2NZ8B1S
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hr...				J Med Chem 62: 491-511 (2019) Article DOI: 10.1021/acs.jmedchem.8b00973 BindingDB Entry DOI: 10.7270/Q2GF0XZ5
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00943 BindingDB Entry DOI: 10.7270/Q2DV1PHB
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of androgen receptor (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112667 BindingDB Entry DOI: 10.7270/Q2HD80BX
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of California US Patent					Assay Description Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...				US Patent US10053433 (2018) BindingDB Entry DOI: 10.7270/Q2R78H77
The Regents of the University of California US Patent					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of California US Patent					Assay Description Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...				US Patent US10053433 (2018) BindingDB Entry DOI: 10.7270/Q2R78H77
The Regents of the University of California US Patent					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50094975 (956104-40-8 \| ARN-509 \| JNJ-56021927 \| US10053433,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of California US Patent					Assay Description An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...				US Patent US10053433 (2018) BindingDB Entry DOI: 10.7270/Q2R78H77
The Regents of the University of California US Patent					More data for this Ligand-Target Pair