BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50435990'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50435990 (GALETERONE \| TOK-001 \| US9611270, galaterone \| VN/...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01164 BindingDB Entry DOI: 10.7270/Q2251P5V
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50435990 (GALETERONE \| TOK-001 \| US9611270, galaterone \| VN/...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	405	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from androgen receptor in human PC3 cells				J Med Chem 58: 2077-87 (2015) Article DOI: 10.1021/jm501239f BindingDB Entry DOI: 10.7270/Q2MS3VFF
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50435990 (GALETERONE \| TOK-001 \| US9611270, galaterone \| VN/...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars		n/a	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50435990 (GALETERONE \| TOK-001 \| US9611270, galaterone \| VN/...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	845	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from androgen receptor in human LNCAP cells				J Med Chem 58: 2077-87 (2015) Article DOI: 10.1021/jm501239f BindingDB Entry DOI: 10.7270/Q2MS3VFF
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50435990 (GALETERONE \| TOK-001 \| US9611270, galaterone \| VN/...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysis				J Med Chem 56: 4880-98 (2013) Article DOI: 10.1021/jm400048v BindingDB Entry DOI: 10.7270/Q2445NWN
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair