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Found 1 hit Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50535830'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Rattus norvegicus (Rat))		BDBM50535830
PNG
(CHEMBL4523011)
Show SMILES CC(O)(COc1ccc(cc1C(F)(F)F)C#N)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C19H13F6N3O5/c1-17(30,9-33-15-5-2-10(8-26)6-13(15)19(23,24)25)16(29)27-11-3-4-14(28(31)32)12(7-11)18(20,21)22/h2-7,30H,9H2,1H3,(H,27,29)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 72n/an/an/an/an/an/a



School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ...

Eur J Med Chem 118: 230-43 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N
More data for this
Ligand-Target Pair