Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor [776-1124]' and Ligand = 'BDBM239563'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human))	BDBM239563 (US9394309, 16) Show SMILES Cc1nccn1-c1cc(cc(c1)S(F)(F)(F)(F)F)C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C28H22F5N7OS/c1-18-5-6-22(14-26(18)39-10-11-40-27(39)16-25(37-40)20-4-3-7-34-17-20)36-28(41)21-12-23(38-9-8-35-19(38)2)15-24(13-21)42(29,30,31,32)33/h3-17H,1-2H3,(H,36,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human))	BDBM239563 (US9394309, 16) Show SMILES Cc1nccn1-c1cc(cc(c1)S(F)(F)(F)(F)F)C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C28H22F5N7OS/c1-18-5-6-22(14-26(18)39-10-11-40-27(39)16-25(37-40)20-4-3-7-34-17-20)36-28(41)21-12-23(38-9-8-35-19(38)2)15-24(13-21)42(29,30,31,32)33/h3-17H,1-2H3,(H,36,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	9.6	4
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For measuring the autophosphorylation of the endogenous Tie2 receptor in the cell lysates prepared, a self-prepared anti-Tie2 antibody directed again...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
					More data for this Ligand-Target Pair