Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor [776-1124]' and Ligand = 'BDBM239570'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human))	BDBM239570 (US9394309, 23) Show SMILES Cc1ccc(NC(=O)c2cc(OCCCN)cc(c2)S(F)(F)(F)(F)F)cc1-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C27H25F5N6O2S/c1-18-5-6-21(14-25(18)37-9-10-38-26(37)16-24(36-38)19-4-2-8-34-17-19)35-27(39)20-12-22(40-11-3-7-33)15-23(13-20)41(28,29,30,31)32/h2,4-6,8-10,12-17H,3,7,11,33H2,1H3,(H,35,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
					More data for this Ligand-Target Pair