Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor [776-1124]' and Ligand = 'BDBM239582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human))	BDBM239582 (US9394309, 35) Show SMILES Cc1ccc(NC(=O)c2cc(CN3CCNCC3)cc(c2)S(F)(F)(F)(F)F)cc1-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C29H28F5N7OS/c1-20-4-5-24(16-27(20)40-11-12-41-28(40)17-26(38-41)22-3-2-6-36-18-22)37-29(42)23-13-21(19-39-9-7-35-8-10-39)14-25(15-23)43(30,31,32,33)34/h2-6,11-18,35H,7-10,19H2,1H3,(H,37,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
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