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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor [776-1124]' and Ligand = 'BDBM239687'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiopoietin-1 receptor [776-1124]


(Homo sapiens (Human))		BDBM239687
PNG
(US9394309, 144)
Show SMILES Cc1cc(C)c(cc1NC(=O)c1cc(cc(c1)S(F)(F)(F)(F)F)N1CCC(CC1)C#N)-n1ccn2nc(cc12)-c1cccnc1
Show InChI InChI=1S/C31H28F5N7OS/c1-20-12-21(2)29(42-10-11-43-30(42)17-28(40-43)23-4-3-7-38-19-23)16-27(20)39-31(44)24-13-25(41-8-5-22(18-37)6-9-41)15-26(14-24)45(32,33,34,35)36/h3-4,7,10-17,19,22H,5-6,8-9H2,1-2H3,(H,39,44)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.600n/an/an/an/a7.022



Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH

US Patent


Assay Description
For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...

US Patent US9394309 (2016)


BindingDB Entry DOI: 10.7270/Q2C53JRC
More data for this
Ligand-Target Pair