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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM447686'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447686
PNG
(US10689367, Example 6.0)
Show SMILES COCC(COC)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C21H28ClN7O6S/c1-13(18(35-5)19-23-9-14(22)10-24-19)36(30,31)28-21-27-26-20(16-7-6-8-17(25-16)34-4)29(21)15(11-32-2)12-33-3/h6-10,13,15,18H,11-12H2,1-5H3,(H,27,28)/t13-,18-/m0/s1
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US Patent
n/an/an/an/a 0.300n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair