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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM456867'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM456867
PNG
(US10736883, Example 383.0)
Show SMILES COc1ncnc(OC)c1\N=C(\NNC(=O)c1ccc(C)o1)NS(=O)(=O)[C@@H](C)[C@H](C)c1ncc(Cl)cn1 |r|
Show InChI InChI=1S/C21H25ClN8O6S/c1-11-6-7-15(36-11)18(31)28-29-21(27-16-19(34-4)25-10-26-20(16)35-5)30-37(32,33)13(3)12(2)17-23-8-14(22)9-24-17/h6-10,12-13H,1-5H3,(H,28,31)(H2,27,29,30)/t12-,13-/m0/s1
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PC cid
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US Patent
n/an/an/an/a 0.0600n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...

US Patent US10736883 (2020)


BindingDB Entry DOI: 10.7270/Q2JW8HXW
More data for this
Ligand-Target Pair