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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM50506027'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM50506027
PNG
(CHEMBL4587131)
Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1C(=O)Nc1ccc(OC)c(F)c1)c1ccccc1 |r|
Show InChI InChI=1S/C32H28ClFN2O5/c1-3-7-28(19-8-5-4-6-9-19)36-30(37)20-10-13-23(26(16-20)32(39)40)25-17-21(33)11-14-24(25)31(38)35-22-12-15-29(41-2)27(34)18-22/h4-6,8-18,28H,3,7H2,1-2H3,(H,35,38)(H,36,37)(H,39,40)/t28-/m1/s1
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Article
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n/an/an/an/a 0.330n/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...

J Med Chem 62: 10456-10465 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01513
BindingDB Entry DOI: 10.7270/Q2RN3C5X
More data for this
Ligand-Target Pair