Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apelin receptor (Homo sapiens (Human)) | BDBM50556826 (CHEMBL4745863) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [Glp65, Nle75, Tyr77][125I]-apelin13 from human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting based rad... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01913 BindingDB Entry DOI: 10.7270/Q2BG2SNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Rattus norvegicus) | BDBM50556826 (CHEMBL4745863) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at APJ receptor in rat NRK-52E cells assessed as effect on cAMP accumulation incubated for 1 hr by cAMP-Glo assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01913 BindingDB Entry DOI: 10.7270/Q2BG2SNB | |||||||||||
More data for this Ligand-Target Pair |