Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N]' and Ligand = 'BDBM577701'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N] (Homo sapiens (Human))	BDBM577701 ((rac)-3-chloro-4-ethyl-14-{3-[(6-fluoronaphthalen-...) Show SMILES CCc1c-2c(COCC3CC3Cn3c(C(O)=O)c(CCCOc4cccc5cc(F)ccc45)c4ccc(Cl)c-2c34)nn1C Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NG4TXW
					More data for this Ligand-Target Pair