Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50234314'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50234314 (CHEMBL4063192) Show SMILES Cc1ccc(Nc2nnc(o2)-c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H14N4O/c1-11-6-8-12(9-7-11)19-17-21-20-16(22-17)14-10-18-15-5-3-2-4-13(14)15/h2-10,18H,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of biotinylated Bim peptide binding to His-tagged Bcl-2 (unknown origin) preincubated for 1 hr followed by biotinylated Bim peptide additi...				Bioorg Med Chem Lett 27: 1037-1040 (2017) Article DOI: 10.1016/j.bmcl.2016.12.061 BindingDB Entry DOI: 10.7270/Q28C9ZG5
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