Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50511124![]() (CHEMBL4533559) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged human Bcl-2 isoform 2 (1 to 34 residues and 92 to 202 residues with Bcl-xL sequence (35 to 50 residues) expresse... | J Med Chem 63: 2489-2510 (2020) Article DOI: 10.1021/acs.jmedchem.9b01442 BindingDB Entry DOI: 10.7270/Q2542RW2 | |||||||||||
More data for this Ligand-Target Pair |