Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50541349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50541349 (CHEMBL4646811) Show SMILES CC1(C)CCCC2=C1C[C@@H]([C@H](C2)c1ccccc1)C(O)=O |r,c:6| Show InChI InChI=1S/C19H24O2/c1-19(2)10-6-9-14-11-15(13-7-4-3-5-8-13)16(18(20)21)12-17(14)19/h3-5,7-8,15-16H,6,9-12H2,1-2H3,(H,20,21)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127003 BindingDB Entry DOI: 10.7270/Q2445R24
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