Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM164985'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164985 (US9067917, 18 | US9682971, 18) Show SMILES Cc1nc(no1)-c1ccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C34H31N5O4/c1-21-35-32(38-43-21)24-12-10-22(11-13-24)19-39-31-17-16-26(42-20-25-15-14-23-6-2-5-9-29(23)36-25)18-30(31)37-33(39)27-7-3-4-8-28(27)34(40)41/h2,5-6,9-18,27-28H,3-4,7-8,19-20H2,1H3,(H,40,41)/t27?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164985 (US9067917, 18 | US9682971, 18) Show SMILES Cc1nc(no1)-c1ccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C34H31N5O4/c1-21-35-32(38-43-21)24-12-10-22(11-13-24)19-39-31-17-16-26(42-20-25-15-14-23-6-2-5-9-29(23)36-25)18-30(31)37-33(39)27-7-3-4-8-28(27)34(40)41/h2,5-6,9-18,27-28H,3-4,7-8,19-20H2,1H3,(H,40,41)/t27?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair