Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM165060'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165060 (US9067917, 95 | US9682971, 95) Show SMILES COc1ccc(cn1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C37H34N4O4/c1-44-35-16-12-28(22-38-35)27-9-6-7-25(19-27)23-41-33-15-14-30(45-24-29-13-11-26-8-2-3-10-31(26)39-29)20-32(33)40-34(41)21-37(36(42)43)17-4-5-18-37/h2-3,6-16,19-20,22H,4-5,17-18,21,23-24H2,1H3,(H,42,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165060 (US9067917, 95 | US9682971, 95) Show SMILES COc1ccc(cn1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C37H34N4O4/c1-44-35-16-12-28(22-38-35)27-9-6-7-25(19-27)23-41-33-15-14-30(45-24-29-13-11-26-8-2-3-10-31(26)39-29)20-32(33)40-34(41)21-37(36(42)43)17-4-5-18-37/h2-3,6-16,19-20,22H,4-5,17-18,21,23-24H2,1H3,(H,42,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair