Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM165063'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165063 (US9067917, 98 | US9682971, 98) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2cscn2)CCCC1 Show InChI InChI=1S/C34H30N4O3S/c39-33(40)34(14-3-4-15-34)18-32-37-29-17-27(41-20-26-11-10-24-7-1-2-9-28(24)36-26)12-13-31(29)38(32)19-23-6-5-8-25(16-23)30-21-42-22-35-30/h1-2,5-13,16-17,21-22H,3-4,14-15,18-20H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165063 (US9067917, 98 | US9682971, 98) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)-c2cscn2)CCCC1 Show InChI InChI=1S/C34H30N4O3S/c39-33(40)34(14-3-4-15-34)18-32-37-29-17-27(41-20-26-11-10-24-7-1-2-9-28(24)36-26)12-13-31(29)38(32)19-23-6-5-8-25(16-23)30-21-42-22-35-30/h1-2,5-13,16-17,21-22H,3-4,14-15,18-20H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair