Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM165105'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165105 (US9067917, 140 | US9682971, 140) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C38H31F4N3O3/c39-32-19-25(23-11-14-27(15-12-23)38(40,41)42)9-10-26(32)21-45-35-18-17-29(48-22-28-16-13-24-5-1-4-8-33(24)43-28)20-34(35)44-36(45)30-6-2-3-7-31(30)37(46)47/h1,4-5,8-20,30-31H,2-3,6-7,21-22H2,(H,46,47)/t30?,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165105 (US9067917, 140 | US9682971, 140) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C38H31F4N3O3/c39-32-19-25(23-11-14-27(15-12-23)38(40,41)42)9-10-26(32)21-45-35-18-17-29(48-22-28-16-13-24-5-1-4-8-33(24)43-28)20-34(35)44-36(45)30-6-2-3-7-31(30)37(46)47/h1,4-5,8-20,30-31H,2-3,6-7,21-22H2,(H,46,47)/t30?,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair