Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM168631'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM168631 (US9079866, 4 | US9745328, Compound 4 | US9884878, ...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1 Show InChI InChI=1S/C20H21FN4O2S/c1-20(2,3)25-28(26,27)18-7-5-4-6-14(18)13-8-9-15(16(21)10-13)17-11-24-19(22)12-23-17/h4-12,25H,1-3H3,(H2,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9884878 (2018) BindingDB Entry DOI: 10.7270/Q2R78H8P
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM168631 (US9079866, 4 | US9745328, Compound 4 | US9884878, ...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1 Show InChI InChI=1S/C20H21FN4O2S/c1-20(2,3)25-28(26,27)18-7-5-4-6-14(18)13-8-9-15(16(21)10-13)17-11-24-19(22)12-23-17/h4-12,25H,1-3H3,(H2,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9079866 (2015) BindingDB Entry DOI: 10.7270/Q2FF3R3Q
					More data for this Ligand-Target Pair